Hypervalent Iodine‐Mediated Azidation Reactions

Organic azides have found wide application in various fields of science and technology. This review summarizes recently developed approaches to the direct, one-step synthesis diverse organic utilizing hypervalent iodine reagents. The first part deals with azidation using unstable azidoiodinanes generated situ from common reagents (such as diacetoxyiodobenzene or iodosylbenzene) a source azide anion (TMSN3 NaN3). second is dedicated stable azidobenziodoxoles useful azidating that allow selective direct C−H bonds double carbon-carbon under mild reaction conditions. use eliminates main disadvantages traditional azides, such need pre-functionalization substrates harsh Synthetic made possible plethora including complex molecules at late synthetic stage.